Tigranes the Great (Armenian: Տիգրան Մեծ, EA: Tigran Mets, WA: Dikran Medz, Greek: Τιγράνης ο Μέγας) (ruled 95 BCE–55 BCE) (also called Tigranes II and sometimes Tigranes I) was a king of Armenia under whom the country became, for a short time, the strongest state east of the Roman Republic. Tigranes was born around 140 BCE and was the son or nephew of either Artavasdes I or Tigranes I. Tigranes the Great represented the Artaxiad Royal House. He was married to Cleopatra, daughter of Mithridates VI of Pontus.

He was involved in many battles during his reign against opponents such as the Parthian and Seleucid empires, and the Roman Republic.